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Cat. Number
SJN 2511
Chemical Name
SJN 2511
CAS Number
[446859-33-2]
Mol. Formula
C17H13N5
Mol. Weight
287.32
Qty 1
10mg
Qty 2
50mg
Synonym
2-(3-(6-Methylpyridine-2-yl)-1H-pyr azol-4-yl)-1,5-naphthyridine
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at +4°C
References
Selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). Selective for ALK5 over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). Enhances the efficiency of cellular reprogramming.
Purity: >99 %
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