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/ Products Classification 点击展开+Cat. Number | SJN 2511 |
Chemical Name | SJN 2511 |
CAS Number | [446859-33-2] |
Mol. Formula | C17H13N5 |
Mol. Weight | 287.32 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-(3-(6-Methylpyridine-2-yl)-1H-pyr azol-4-yl)-1,5-naphthyridine |
Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
Storage condition | Store at +4°C |
References | Selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). Selective for ALK5 over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). Enhances the efficiency of cellular reprogramming. Purity: >99 % |