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/ Products Classification 点击展开+Cat. Number | Sivelestat sodium salt |
Chemical Name | Sivelestat sodium salt |
CAS Number | [150374-95-1] |
Mol. Formula | C20H21N2NaO7S |
Mol. Weight | 456.44 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-{2-[({4-[(2,2-Dimethylpropanoyl)o xy]phenyl}sulfonyl)amino]benzoyl}glycine sodium salt |
Solubility | Soluble to 50 mM in DMSO |
Storage condition | Desiccate at RT |
References | Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil transmigration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo. Purity: >98 % |