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Cat. Number
SHU 9119
Chemical Name
SHU 9119
CAS Number
[168482-23-3]
Mol. Formula
C54H71N15O9
Mol. Weight
1074.25
Qty 1
1mg
Storage condition
Store at -20°C
References
Potent melanocortin MC3 and MC4 receptor antagonist (IC50 values are 0.23 and 0.06 nM respectively) and MC5 partial agonist (EC50 = 0.12 nM). Upregulates expression of genes promoting lipogenesis and triglyceride storage (SCD1, LPL, ACCα and FAS), increases triglyceride synthesis and promotes insulin resistance. Increases food intake, body weight and fat mass when administered centrally in vivo.
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