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Cat. Number
SecinH3
Chemical Name
SecinH3
CAS Number
[853625-60-2]
Mol. Formula
C24H20N4O4S
Mol. Weight
460.5
Qty 1
10mg
Qty 2
50mg
Synonym
N-[4-[5-(1,3-Benzodioxol-5-yl)-3-me thoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio) acetamide
Solubility
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage condition
Store at +4°C
References
Sec7-specific GEF inhibitor that displays selectivity for small GEFs of the cytohesin family (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, yGea2-S7 and hEFA6-S7 respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation.
Purity: >99 %
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