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/ Products Classification 点击展开+Cat. Number | SecinH3 |
Chemical Name | SecinH3 |
CAS Number | [853625-60-2] |
Mol. Formula | C24H20N4O4S |
Mol. Weight | 460.5 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[4-[5-(1,3-Benzodioxol-5-yl)-3-me thoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio) acetamide |
Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
Storage condition | Store at +4°C |
References | Sec7-specific GEF inhibitor that displays selectivity for small GEFs of the cytohesin family (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, yGea2-S7 and hEFA6-S7 respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation. Purity: >99 % |
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