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Cat. Number
SDZ NKT 343
Chemical Name
SDZ NKT 343
CAS Number
[180046-99-5]
Mol. Formula
C33H33N5O5
Mol. Weight
579.65
Qty 1
10mg
Synonym
1-[[(2-Nitrophenyl)amino]carbonyl]- L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmeth yl)-L-alaninamide
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Highly selective human tachykinin NK1 receptor antagonist (IC50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK2 and NK3 receptors. Potently antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo.
Purity: >98 %
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