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| Cat. Number | Sazetidine A dihydrochloride |
| Chemical Name | Sazetidine A dihydrochloride |
| CAS Number | [820231-95-6] |
| Mol. Formula | C15H22Cl2N2O2 |
| Mol. Weight | 333.25 |
| Qty 1 |
10mg |
| Synonym | 6-[5-[(2S)-2-Azetidinylmethoxy]-3-p yridinyl]-5-hexyn-1-ol dihydrochloride |
| Solubility | Soluble to 50 mM in water |
| Storage condition | Desiccate at +4°C |
| References | Subtype-selective α4β2 nicotinic acetylcholine receptor ligand (Ki values are 0.26 and 54 nM at α4β2 and α3β4 receptors respectively). May act as a silent desensitizer or as an agonist (EC50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo and significantly reduces nicotine self-administration in an experimental rat model. Purity: >98 % |
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