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| Cat. Number | SANT-1 |
| Chemical Name | SANT-1 |
| CAS Number | [304909-07-7] |
| Mol. Formula | C23H27N5 |
| Mol. Weight | 373.5 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[(3,5-dimethyl-1-phenyl-1H-pyrazo l-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamin e |
| Solubility | Soluble to 25 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells). Purity: >99 % |
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