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Cat. Number
S 14506 hydrochloride
Chemical Name
S 14506 hydrochloride
CAS Number
[135721-98-1]
Mol. Formula
C24H26FN3O2.HCl
Mol. Weight
443.94
Qty 1
10mg
Qty 2
50mg
Synonym
4-Fluoro-N-[2-[4-(7-methoxy-1-napht halenyl)-1-piperazinyl]ethyl]benzamide hydrochloride
Solubility
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo.
Purity: >99 %
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