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| Cat. Number | TW 37 |
| Chemical Name | TW 37 |
| CAS Number | [877877-35-5] |
| Mol. Formula | C33H35NO6S |
| Mol. Weight | 573.7 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[4-[[2-(1,1-Dimethylethyl)phenyl] sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methyle thyl)phenyl]methyl]benzamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11 μM for Bcl-2 and Bcl-XL respectively). Inhibits the angiogenic potential of endothelial cells in vitro. Induces S-phase arrest and apoptosis in pancreatic cancer cell lines; also inhibits the activation of Notch-1 and Jagged-1 in vitro and in vivo. Purity: >97 % |
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