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| Cat. Number | Tetrabenazine |
| Chemical Name | Tetrabenazine |
| CAS Number | [58-46-8] |
| Mol. Formula | C19H27NO3 |
| Mol. Weight | 317.2 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (3R,11bR)-rel-1,3,4,6,7,11b-hexahyd ro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]qu inolizin-2-one |
| Solubility | Soluble to 30 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice. Purity: >99 % |
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