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| Cat. Number | Terfenadine |
| Chemical Name | Terfenadine |
| CAS Number | [50679-08-8] |
| Mol. Formula | C32H41NO2 |
| Mol. Weight | 471.67 |
| Qty 1 |
50mg |
| Synonym | α-[4-(1,1-Dimethylethyl)phenyl]-4-(h ydroxydiphenylmethyl)-1-piperidinebutanol |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Histamine H1 receptor antagonist. Also blocks hERG and KATP channels (IC50 values are 204 nM and 1.2 μM respectively). Inhibits the delayed rectifier K+ current (IKr) in guinea pig ventricular myocytes (IC50 = 50 nM). Activity prolongs QT and induces Torsades de pointes (TdP); cardiotoxic in vivo. Purity: >98 % |
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