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| Cat. Number | TCS JNK 6o |
| Chemical Name | TCS JNK 6o |
| CAS Number | [894804-07-0] |
| Mol. Formula | C18H20N4O4 |
| Mol. Weight | 356.38 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(4-Amino-5-cyano-6-ethoxy-2-pyrid inyl)-2,5-dimethoxybenzeneacetamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays > 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro. Purity: >98 % |
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