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| Cat. Number | TCS 2312 dihydrochloride |
| Chemical Name | TCS 2312 dihydrochloride |
| CAS Number | [838823-32-8] |
| Mol. Formula | C25H24N4O2.2HCl |
| Mol. Weight | 485.41 |
| Qty 1 |
1mg |
| Synonym | 4'-[5-[[3-[(Cyclopropylamino)methyl] phenyl]amino]-1H-pyrazol-3-yl]-[1,1'-biphenyl]-2,4- diol dihydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent and selective checkpoint kinase 1 (chk1) inhibitor (Ki = 0.38 nM, EC50 = 60 nM). Enhances the cell killing activity of Gemcitabine (Cat. No. 3259) in breast and prostate cancer cell lines and displays antiproliferative effects in vitro. Purity: >97 % |
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