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Cat. Number
DL-TBOA
Chemical Name
DL-TBOA
Mol. Formula
C11H13NO5
Mol. Weight
239.23
Qty 1
10mg
Qty 2
50mg
Synonym
DL-threo-β-Benzyloxyaspartic acid
Solubility
Soluble to 100 mM in DMSO and to 5 mM in water
Storage condition
Desiccate at -20°C
References
A competitive, non-transportable blocker of excitatory amino acid transporters (IC50 values are 70, 6, and 6 μM for EAAT1, EAAT2 and EAAT3 respectively). Also inhibits EAAT4 and EAAT5 (Ki values are 4.4 and 3.2 μM respectively). Displays high selectivity for EAATs over ionotropic and metabotropic glutamate receptors. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™.
Purity: >98 %
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