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| Cat. Number | UK 370106 |
| Chemical Name | UK 370106 |
| CAS Number | [230961-21-4] |
| Mol. Formula | C35H44N2O5 |
| Mol. Weight | 572.73 |
| Qty 1 |
10mg |
| Synonym | (βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1- phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]ami no]carbonyl]-2-methyl-[1,1'-biphenyl]-4-hexanoic acid |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Highly selective MMP-3 and MMP-12 inhibitor (IC50 values are 0.023, 0.042, 1.75, 2.3, 5.8, 30.4, 34.2 and 66.9 μM at MMP 3, 12, 8, 13, 7, 9, 2 and 14 respectively.) Inhibits fibronectin cleavage (IC50 = 320 nM) and has little effect on keratinocyte migration in vitro. Substantially inhibits MMP-3 in an ex vivo model of chronic dermal ulcers. Purity: >97 % |
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