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Cat. Number
UCB 35625
Chemical Name
UCB 35625
CAS Number
[301648-08-8]
Mol. Formula
C30H37Cl2IN2O2
Mol. Weight
655.44
Qty 1
1mg
Qty 2
10mg
Synonym
1,4-trans-1-(1-Cycloocten-1-ylmethy l)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amin o]-1-ethylpiperidinium iodide
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at +4°C
References
Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM). Isomer of J 113863 (Cat. No. 2595).
Purity: >98 %
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