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/ Products Classification 点击展开+Cat. Number | UCB 35625 |
Chemical Name | UCB 35625 |
CAS Number | [301648-08-8] |
Mol. Formula | C30H37Cl2IN2O2 |
Mol. Weight | 655.44 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Synonym | 1,4-trans-1-(1-Cycloocten-1-ylmethy l)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amin o]-1-ethylpiperidinium iodide |
Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
Storage condition | Store at +4°C |
References | Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM). Isomer of J 113863 (Cat. No. 2595). Purity: >98 % |