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| Cat. Number | VX 745 |
| Chemical Name | VX 745 |
| CAS Number | [209410-46-8] |
| Mol. Formula | C19H9Cl2F2N3OS |
| Mol. Weight | 436.26 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5-(2,6-Dichlorophenyl)-2-[2,4-diflu orophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Highly potent and selective p38α inhibitor (IC50 = 10 nM). Also blocks TNFα production in LPS-stimulated HWB in vitro (IC50 = 177 nM). Displays 1000-fold selectivity over closely related kinases, including ERK1, MK2 and JNK1-3. Purity: >98 % |
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