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Cat. Number
VU 591 hydrochloride
Chemical Name
VU 591 hydrochloride
Mol. Formula
C16H12N6O5
Mol. Weight
368.3
Qty 1
10mg
Qty 2
50mg
Synonym
6-Nitro-2-[(6-nitro-1H-benzimidazol -2-yl)methoxymethyl]-1H-benzimidazole hydrochloride
Solubility
Soluble to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Selective renal outer medullary potassium channel (ROMK, Kir1.1) antagonist (IC50 = 300 nM). Thought to block the intracellular pore of the ROMK channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590 (Cat. No. 3891).
Purity: >99 %
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