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Cat. Number
WRW4
Chemical Name
WRW4
Mol. Formula
C61H65N15O6
Mol. Weight
1104.28
Qty 1
1mg
Storage condition
Desiccate at -20°C
References
Selective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β42 peptide.
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