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Cat. Number
Withaferin A
Chemical Name
Withaferin A
CAS Number
[5119-48-2]
Mol. Formula
C28H38O6
Mol. Weight
470.6
Qty 1
1mg
Synonym
(4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihy droxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone
Solubility
Soluble in DMSO and in ethanol
Storage condition
Desiccate at -20°C
References
Steroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) spouting in vitro (IC50 = 12 nM) and in vivo. Prevents NF-κB activation by inhibiting activation of IKKβ. Also inhibits chymotrypsin-like activity of the 20S proteasome.
Purity: >98 %
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