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| Cat. Number | ZK 756326 |
| Chemical Name | ZK 756326 |
| CAS Number | [874911-96-3] |
| Mol. Formula | C21H28N2O3.2HCl |
| Mol. Weight | 429.38 |
| Synonym | 2-[2-[4-[(3-phenoxyphenyl)methyl]-1 -piperazinyl]ethoxy]ethanol dihydrochloride |
| Solubility | Soluble to 100 mM in water |
| Storage condition | Desiccate at RT |
| References | Selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. Purity: >99 % |
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