您的位置:首页>>分析化学>>Taxinine M 紫杉宁M
Cat. Number
HT0114
Chemical Name
Taxinine M 紫杉宁M
Mol. Formula
C35H42O14
Mol. Weight
686.70
Qty 1
5mg
Qty 2
25mg
Application Notes
≥98%
Storage condition
-20°C
References

Taxinine M is a taxane compound originally isolated from species of the yew tree under the Taxus genus. Taxinines inhibit DNA polymerase. Taxinine M displays anticancer activity, inhibiting lung cancer cell proliferation. Like other taxanes, taxinine M may also promote microtubule polymerization and prevent microtubule depolymerization.
 

Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

Prasain JK, Stefanowicz P, Kiyota T, et al. Taxines from the needles of Taxus wallichiana. Phytochemistry. 2001 Dec;58(8):1167-70. PMID: 11738401.

Beutler JA, Chmurny GM, Look SA, et al. Taxinine M, a new tetracyclic taxane from Taxus brevifolia. J Nat Prod. 1991 May-Jun;54(3):893-7. PMID: 1955887.

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