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| Cat. Number | 188833256108381 |
| Chemical Name | Ceftriaxone Disodium Hemiheptahydrate |
| CAS Number | 104376-79-6 |
| Mol. Formula | C18H16N8O7S3Na2 • 7/2H2O |
| Mol. Weight | 661.60 |
| Qty 1 |
250mg |
| Qty 2 | 1g |
| Application Notes | ≥98% |
| Synonym | Ceftriaxone disodium slat hemiheptahydrate, Rocefin, Rocephine |
| Melting Pt. | >155°C |
| Solubility | Soluble in water (40 g/100 ml). DMSO 1 mg/mL. |
| Storage condition | 4°C |
| References | Ceftriaxone is a third generation β-lactam cephalosporin antibiotic. Ceftriaxone exhibits antibacterial efficacy against gram positive and gram negative bacteria, inhibiting penicillin binding protein activity to prevent peptidoglycan synthesis and bacterial cell wall formation. Ceftriaxone is also neuroprotective. This compound displays cognition enhancing benefit, suppressing traumatic brain injury-induced brain edema and cognitive function deficits in animal models by decreasing autophagy and upregulating expression of glutamate transporter GLT-1; this also results in protection in animal models of Huntington’s disease and attenuates the development of dependence and abstinence-induced withdrawal in animal models of substance abuse. |
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