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Cat. Number
HB0025
Chemical Name
巴弗洛霉素A1,Bafilomycin A1
CAS Number
[88899-55-2]
Mol. Formula
C35H58O9
Mol. Weight
622.8
Qty 1
500ug
Qty 2
1mg
Appearance
White to off white powder
Application Notes
≥90%
Synonym
Bafilomycin A1
Solubility
Soluble in DMSO, ethanol and methanol.
Storage condition
-20oC
References

Description

巴弗洛霉素A1 Bafilomycin A1 is a macrolide antibiotic initially produced by Streptomyces that exhibits anti-parasitic, antimalarial, and anticancer chemotherapeutic activities. Bafilomycin A1 inhibits the vacuolar H+ ATPase and suppresses autophagy. Bafilomycin kills Plasmodium parasites in cellular models, and separately, induces cell death and suppresses tumor growth in animal models of breast cancer.


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