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| Cat. Number | 072626136407880 |
| Chemical Name | 柠檬苦素葡萄糖苷 LIMONIN GLUCOSIDE |
| CAS Number | 123564-61-4 |
| Category | Flavonoids |
| Mol. Formula | C32H42O14 |
| Mol. Weight | 650.67 |
| Qty 1 |
1mg |
| Qty 2 | 5mg |
| Appearance | ≥95% |
| Synonym | CCRIS 6986; LIMONIN-17-B-D-GLUCOPYRANOSIDE |
| Solubility | Soluble in methanol, water (5 mg/mL) |
| Storage condition | 4°C |
| References | Limonin is a furanolactone found in fruits in the Citrus family. Limonin exhibits antioxidative, anti-inflammatory, hepatoprotective, anticancer, antiviral, anti-parasitic, and immunomodulatory activities. In animal models of hepatic ischemia/reperfusion, limonin upregulates expression of IL-10 and downregulates expression of toll-like receptors 2 and 4 (TLR2, TLR4), MyD88, TRIF, TNF-α, and NF-κB. In colon adenocarcinoma cells, limonin induces mitochondria-dependent apoptosis and inhibits proliferation. Additionally, limonin inhibits expression of HIV-1 and HTLV-1 in infected cells. This compound also exhibits larvicidal activity against species of Aedes and decreases NF-κB activation and CD4+ T cell stimulation in vitro. |
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