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Cat. Number
733987962669229
Chemical Name
Zofenopril Calcium Salt
CAS Number
81938-43-4
Category
Inhibitors, MTS & Sulfhydryl Active Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C44H44CaN2O8S4
Mol. Weight
897.17
Qty 1
10mg
Qty 2
100mg
Appearance
White to Off-White Solid
Application Notes
Angiotensin-converting enzyme ACE inhibitor. A prodrug that is de-esterified to the active inhibitor, the sulfhydryl group containing metabolite, Zofenoprilat.
Synonym
[1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl Ester Calcium Salt; Bifril-d5; Zofenil;
Melting Pt.
249-251°C
Solubility
DMSO, Methanol (Sparingly)
Storage condition
Refrigerator
References
Gorren, A., et al.: Biochem. J., 331, 801 (1998), Subissi, A., et al.: Cardivascular Drug Reviews, 17, 2 (1999), Marchand, C., et al.: Mol. Pharmacol., 64, 600 (2003), Maurin, C., et al.: J. Med. Chem., 47, 5583 (2004),
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