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Cat. Number
733986731606624
Chemical Name
(R)-(+)-Thalidomide
CAS Number
2614-06-4
Category
Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C13H10N2O4
Mol. Weight
258.23
Qty 1
10mg
Qty 2
100mg
Appearance
Needles
Application Notes
Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.
Synonym
(R)-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione; (R)-Thalidomide; NSC 91729;
Melting Pt.
269-271°C
Solubility
Sparingly soluble in Water, Methanol, Ethanol, Acetone, Ethyl Acetate, Butyl Acetate
References
D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)
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