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Cat. Number
733986334969288
Chemical Name
Tenofovir Disoproxil Fumarate
CAS Number
202138-50-9
Category
Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Phosphorylating and Phosphitylating Agents
Mol. Formula
C23H34N5O14P
Mol. Weight
635.51
Qty 1
10mg
Qty 2
100mg
Appearance
White Solid
Application Notes
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
Synonym
5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid� 1,9-Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate; GS 4331-05; PMPA Prodrug; Tenofovir DF; Virea; Viread;
Melting Pt.
113-115°C
Solubility
DMSO
Storage condition
Refrigerator
References

 

Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997),
Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),
Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006),
Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

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