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Cat. Number
733986710713558
Chemical Name
Tenofovir
CAS Number
147127-20-6
Category
Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Phosphorylating and Phosphitylating Agents
Mol. Formula
C9H14N5O4P
Mol. Weight
287.21
Qty 1
5mg
Qty 2
50mg
Appearance
White to Off-White Solid
Application Notes
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
Synonym
[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid; (R)-9-(2-Phosphonomethoxypropyl)adenine; (R)-PMPA; GS-1278; Tenefovir;
Melting Pt.
280-282°C
Solubility
DMSO, Warm Water
Storage condition
-20?C Freezer
References
Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),
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