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Cat. Number
733985275159177
Chemical Name
Tazarotene
CAS Number
118292-40-3
Category
Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Retinoids, Sulfur & Selenium Compounds
Mol. Formula
C21H21NO2S
Mol. Weight
351.46
Qty 1
10mg
Qty 2
100mg
Appearance
Light Yellow Solid
Application Notes
An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.
Synonym
6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic Acid Ethyl Ester; AGN 190168; Tazorac; Zorac;
Melting Pt.
95-98°C
Solubility
Chloroform, Methanol
Storage condition
Refrigerator
References
Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),
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