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Cat. Number
733985922350513
Chemical Name
Tarceva Hydrochloride (Erlotinib Hydrochloride)
CAS Number
183319-69-9
Category
Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C22H24ClN3O4
Mol. Weight
429.90
Qty 1
5mg
Qty 2
50mg
Appearance
Off-White Solid
Application Notes
Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.
Synonym
[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine; N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine; Erlotinib Hydrochloride;
Melting Pt.
223-225°C
Boiling Pt.
N/A
Solubility
Acetic Acid, Dimethylformamide, Dimethyl Sulfoxide, Methanol (Sparingly)
References
Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),
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