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Cat. Number
733985654989883
Chemical Name
Tamoxifen N-Oxide
CAS Number
75504-34-6
Category
Aromatics, Metabolites & Impurities, Nitric Oxide Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C26H29NO2
Mol. Weight
387.51
Qty 1
10mg
Qty 2
100mg
Appearance
White Solid
Application Notes
A metabolite of Tamoxifen (T006000), a nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines.
Synonym
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine N-Oxide;
Storage condition
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
References
Brandt, S., et al.: Anticancer Res., 23, 223 (2003), Coller, J., et al.: Br. J. Clin. Pharmacol., 57, 105 (2004), Parte, P., et al.: Drug Metab. Dispos., 33, 1446 (2005),
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