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Cat. Number
733985978153703
Chemical Name
Tamoxifen-d5
Category
Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Mol. Formula
C26H24D5NO
Mol. Weight
376.55
Qty 1
1mg
Qty 2
10mg
Appearance
Pale Brown Cyrstals
Application Notes
Labelled Tamoxifen (T006000). A nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a protein kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines.
Synonym
(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-butene-3,3,4,4,4-d5; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine-d5; ICI 47699-d5; Mammaton-d5; Novaldex-d5; Tamoxifen-d5; Z-Tamoxifen-d5; trans-Tamoxifen-d5;
Melting Pt.
95-97°C
Solubility
Chloroform, Dichlormethane, Ethanol, Methanol
Storage condition
-20?C Freezer
References
Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),
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