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Cat. Number
733985481284863
Chemical Name
Taltirelin
CAS Number
103300-74-9
Category
Chiral Reagents, Heterocycles, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C17H23N7O5
Mol. Weight
405.41
Qty 1
10mg
Qty 2
100mg
Application Notes
Analog of thyrotropin releasing hormone TRH, with pronounced CNS activity. Used in the treatment of spinocerebellar degeneration.
Synonym
(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide; (S)-N-(1Methyl-4,5-dihydroorotyl)-L-histidyl-L-prolinamide; TA 0910;
References
Yamamura, M., et al.: Jpn. J. Pharmacol., 53, 451 (1990), Iwasaki, Y., et al.: Neurol. Res., 19, 613 (1997), Kinoshita, K., et al.: CNS Drug Rev., 4, 25 (1998), Morikawa, S., et al.: J. Pharm. Biomed. Anal., 16, 1267 (1998),
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