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Cat. Number
733985122668994
Chemical Name
Suberoylanilide-d5 Hydroxamic Acid
Category
Aromatics, Inhibitors, Isotope Labelled Compounds
Mol. Formula
C14H15D5N2O3
Mol. Weight
269.35
Qty 1
1mg
Qty 2
10mg
Appearance
White Solid
Application Notes
A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
Synonym
SAHA-d5; N-Hydroxy-N’-phenyl-d5-octanediamide; Zolinza-d5;
Melting Pt.
161-162°C
Solubility
Dimethyl Sulfoxide, Methanol
Storage condition
-20?C Freezer
References
Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),
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