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/ Products Classification 点击展开+| Cat. Number | 733985672450029 |
| Chemical Name | Sch 58053 |
| CAS Number | 194423-53-5 |
| Category | Chiral Reagents, Drug Analogues, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol. Formula | C26H23ClFNO3 |
| Mol. Weight | 451.92 |
| Qty 1 |
2.5mg |
| Qty 2 | 25mg |
| Application Notes | An analog of Ezetimibe . SCH 58053 is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine. |
| Synonym | (3R,4β,7α)- 7-(4-Chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)- 2-azaspiro[3.5]nonan-1-one;
|
| References | Ly, H., et al.: Biochem. J., 286, 937 (1992), Dujovne, C., et al.: Am. J. Cardiol., 90, 1092 (2002), Repa, J., et al.: J. Lipid Res., 43, 1864 (2002), Knopp, R., et al.: Eur. Heart J., 24, 729 (2003), Altmann, S., et al.: Science, 303, 1201 (2004), |
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