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Cat. Number
733985559141519
Chemical Name
SB-203580
CAS Number
152121-47-6
Category
Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C21H16FN3OS
Mol. Weight
377.43
Qty 1
25mg
Qty 2
250mg
Appearance
Yellow Solid
Application Notes
A pyridinyl imidazole which acts as a specific inhibitor of p38 MAP kinase. Does not inhibit the MAP kinase homologs JNK and p42 MAP kinase.
Synonym
4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine; 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]pyridine; PB 203580;
Melting Pt.
144-146
Solubility
Acetone, DMSO, Methanol
Storage condition
-20?C Freezer
Stability
-200C
References
Kawasaki, H., et al.: J. Biol. Chem., 272, 18518 (1997), Ward, S.G., et al.: Biochem. Soc. Trans., 245, 304S (1997), Clerk, A., et al.: FEBS Lett., 426, 93 (1998),
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