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/ Products Classification 点击展开+Cat. Number | 733985656446181 |
Chemical Name | Ruboxistaurin Hydrochloride |
CAS Number | 169939-93-9 |
Category | Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
Mol. Formula | C28H29ClN4O3 |
Mol. Weight | 505.01 |
Qty 1 |
25mg |
Application Notes | Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications. |
Synonym | (9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride; LY 333531; |
References |
Ruboxistaurin hydrochloride 是一种选择性的,ATP-竞争性的 PKCβ 抑制剂 |