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Cat. Number
733985646360574
Chemical Name
Roflumilast
CAS Number
162401-32-3
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C17H14Cl2F2N2O3
Mol. Weight
403.21
Qty 1
5mg
Qty 2
50mg
Appearance
White to Off-White Solid
Application Notes
Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.
Synonym
3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107; BY 217; BYK 20869; Daxas;
Melting Pt.
154-158?C
Solubility
Chlorform, DMSO
Storage condition
Refrigerator
References
Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001), Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001), Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002), Rabe, K.F., et al.: Lancet, 366, 563 (2005),
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