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Cat. Number
733985868962286
Chemical Name
Rapamycin-d3 (contains d0) 85%
Category
Chiral Reagents, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C51H76D3NO13
Mol. Weight
917.19
Qty 1
1mg
Qty 2
10mg
Appearance
Pale-Yellow Solid
Application Notes
Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. This compound contains aproximately 2% d0.
Synonym
(-)-Rapamycin-d3; AY 22989-d3; Antibiotic AY 22989-d3; Cypher-d3; NSC 226080-d3; RAPA-d3; RPM-d3; Rapammune-d3; Rapamune-d3; SIIA 9268A-d3; Sirolimus-d3; Wy 090217-d3;
Melting Pt.
101-103°C
Solubility
Dichloromethane, Methanol
Storage condition
-20?C Freezer
Stability
Temperature and Moisture Sensitive
References
Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
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