Heterocycles, Nucleotides, Bases & Related Reagents
Mol. Formula
C8H5N5O
Mol. Weight
187.16
Qty 1
100mg
Qty 2
1g
Application Notes
M1G is a secondary DNA damage product arising from primary reactive oxygen species (ROS) damage to membrane lipids or deoxyribose. It is a guanine adduct formed by reaction of malondialdehyde with DNA.
Synonym
Pyrimido[1,2-a]purin-10(3H)-one ; M1G ;
References
Ham, A., et al.: Chem. Res. Toxicol., 13, 1243 (2000), Sharma, R., et al.: Clin. Cancer Res., 7, 1452 (2001), Jeong, Y., et al.: Chem. Res. Toxicol., 18, 51 (2005),
