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/ Products Classification 点击展开+Cat. Number | 733985859385003 |
Chemical Name | Pyrimethamine |
CAS Number | 58-14-0 |
Category | Amines, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, |
Mol. Formula | C12H13ClN4 |
Mol. Weight | 248.71 |
Qty 1 |
100mg |
Qty 2 | 1g |
Appearance | White Solid |
Application Notes | Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial. |
Synonym | 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine; Chloridin; Chloridine; Daraprim; Khloridin; Malocide; Pirimecidan; Pirimetmin; NSC 3061; RP 4753; |
Melting Pt. | 233-2340C |
Solubility | Ethanol (hot) |
References | Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004), |