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Cat. Number
733985601488646
Chemical Name
N-(4-Pyridyl)-N’-(2,4,6-trichlorophenyl)urea
CAS Number
97627-27-5
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Mol. Formula
C12H8Cl3N3O
Mol. Weight
316.57
Qty 1
5mg
Qty 2
50mg
Appearance
White Solid
Application Notes
A pyridyl urea compound that acts as a potent, selective, and ATP-competitive inhibitor of Rho-associated protein kinase (ROCK).
Synonym
N-4-Pyridinyl-N'-(2,4,6-trichlorophenyl)urea;
Solubility
DMSO
Stability
Light Sensitive
References
Hansch, C., et al.: J. Pharm. Sci., 62, 1 (1973), Pavia, M., et al.: J. Med. Chem., 33, 854 (1990), Sridhar, S., et al.: Eur. J. Pharm. Sci., 16, 129 (2002), Takami, A., et al.: Bioorg. Med. Chem., 12, 2115 (2004),
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