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Cat. Number
733984363085856
Chemical Name
Plevitrexed
CAS Number
153537-73-6
Category
Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C26H25FN8O4
Mol. Weight
532.53
Qty 1
5mg
Qty 2
10mg
Application Notes
A novel non-polyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors.
Synonym
(αS)-α-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid; BGC 9331; NSC 696259; ZD 9331; Vamidex;
References
Sirotnak, F., et al.: Cancer Res., 45, 3992 (1985), Touroutoglou, N., et al.: Clin. Cancer Res., 2, 227 (1996), Twelves, C., et al.: Clin. Cancer Res., 5, 1696 (1999), Goh, B., et al.: J. Clin. Oncol., 19, 1476 (2001),
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