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Cat. Number
733984569261018
Chemical Name
PJ 34 Hydrochloride
CAS Number
344458-15-7
Category
Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C17H18ClN3O2
Mol. Weight
331.80
Qty 1
10mg
Qty 2
100mg
Application Notes
A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. PJ-34 has a lethal effect on breast cancer cells, both in vitro and in vivo, in particular on breast cancer MCF-7.
Synonym
N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)acetamide Hydrochloride; N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-2-(N,N-dimethylamino)acetamide Hydrochloride;
References
Barceloux, D., et al.: Clin. Toxicol., 37, 173 (1999), Dana, F., et al.: J. Med. Chem., 11, 3695 (2003), Besson, V., et al.: Brain Res., 1041, 149 (2005), Szijarto., et al.: J. Surgical Res., 142, 72 (2007),
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