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/ Products Classification 点击展开+Cat. Number | 733984505795392 |
Chemical Name | (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate |
CAS Number | 205393-22-2 |
Category | Boron Derivatives, Chiral Reagents, Intermediates, |
Mol. Formula | C29H39BN4O4 |
Mol. Weight | 518.46 |
Qty 1 |
25mg |
Qty 2 | 250mg |
Appearance | Yellow Semi-Solid |
Application Notes | Intermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate proteasome inhibitor. |
Synonym | N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; |
Solubility | Chloroform, Dimethyl Sulfoxide, Ethanol, Ethyl Acetate, |
References | Zhu, Y., et al.: Bioorg. Med. Chem., 14, 1483 (2006), Dorsey, B., et al.: J. Med. Chem., 51, 1068 (2008), Zhu, Y., et al.: Eur. J .Med. Chem., 44, 1486 (2009), |