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Cat. Number
733984137884968
Chemical Name
(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Hydrochloride
CAS Number
779357-85-6
Category
Amines, Boron Derivatives, Chiral Reagents, Intermediates,
Mol. Formula
C15H29BClNO2
Mol. Weight
301.66
Qty 1
50mg
Qty 2
500mg
Appearance
Off-White Solid
Application Notes
Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.
Synonym
(αR,3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-α-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine Hydrochloride; 3-Methyl-1-(2,9,9-trimethyl-3,5 -dioxa-4-boratricyclo[6.1.1.02,6]dec-4-yl)butylamine Hydrochloride;
Solubility
Dimethylformamide, Ethanol, Methanol, Tetrahydrofuran,
References
Kisselev, A., et al.: Chem. Biol., 8, 739 (2001), Kisselev, A., et al.: J. Biol. Chem., 278, 35869 (2003), Verdoes, M., et al.: Chem. Biol., 13, 1217 (2006),
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