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Cat. Number
733984508932071
Chemical Name
PF 514273
CAS Number
851728-60-4
Category
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C21H17Cl2F2N3O2
Mol. Weight
452.28
Qty 1
10mg
Qty 2
100mg
Application Notes
A novel, bicyclic lactam-based cannabinoid-1 receptor antagonist for the treatment of obesity.
Synonym
2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one;
References
Hao, S., et al.: Eur. J. Pharmacol., 392, 147 (2000), Kershaw, E., et al.: J. Clin. Endocrinol. Metab., 89, 2548 (2004), Engeli, S., et al.: Diabetes, 54, 2838 (2005), Lin, L., et al.: J. Med. Chem., 49, 7584 (2006),
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