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Cat. Number
733983434967848
Chemical Name
Oxamflatin
CAS Number
151720-43-3
Category
Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol. Formula
C17H14N2O4S
Mol. Weight
342.37
Qty 1
5mg
Qty 2
50mg
Application Notes
Histone deacetylase inhibitor. A cell-permeable, aromatic sulfonamide derivative with a hydroxamic acid group that potently inhibits mammalian HDAC by binding to the active site zinc.
Synonym
(2E)-N-Hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-2-penten-4-ynamide; (2E)-5-[3-(Phenylsulfonylamino)phenyl]pent-2-en-4-ynohydroxamic Acid;
References
Ohtani, M., et al.: J. Med. Chem., 39, 2871 (1996), Dear, A.E., et al.: Biochem. Biophys. Acta, 1492, 15 (2000), Lavoie, R., et al.: Bioorg. Med. Chem. Lett., 11, 2847 (2001),
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