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Cat. Number
733983134597673
Chemical Name
Olopatadine N-Oxide
CAS Number
203188-31-2
Category
Amines, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C21H23NO4
Mol. Weight
353.41
Qty 1
2.5mg
Qty 2
25mg
Appearance
White Solid
Application Notes
A metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.
Synonym
11-[3-(Dimethyloxidoamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid;
Melting Pt.
155-157°C
Solubility
Methanol
Storage condition
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
References
Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002), Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2003), Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2004), Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2006),
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